Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, a 48-month program of dietary weight loss and exercise will result in less incident structural knee OA compared to control.

Based on data from nearly 50,000 adults in the United Kingdom, researchers from the U.S. National Institutes of Health have shown an association between dementia risk and daily sedentary behavior. Though the study cannot establish a causal link, it does support the idea that more time spent not moving–such as…

Hip-focused physical therapy for older adults with chronic low back pain, hip pain, and hip muscle weakness may offer promise to address pain-related disability and functional limitations. NIA-funded scientists recently conducted a clinical trial comparing hip- versus back-focused therapies.

Talus fractures are often the result of high-energy mechanisms and can lead to devastating complications. Treatment is often operative; however, the appropriate timing of this has been debated. The purpose of this study was to determine the efficacy and safety of the early treatment of talus fractures.