In an effort to establish an optimal antihypertensive exercise prescription, researchers from Kent, England, conducted a large-scale pairwise and network meta-analysis on the effects of various exercise modes on resting blood pressure. They looked at 270 randomized controlled trials with more than 15,800 patients.
Lower Extremity Review
Inflammatory Markers in Diabetic Foot Infections
This meta-analysis of 10 studies with 785 patients confirmed the significant association between diabetic foot infection and 3 inflammatory markers: white blood cell (WBC) count, C-reactive protein (CRP) level, and procalcitonin (PCT) level. The meta-analysis indicated that mean WBC count (standardized mean differences…
Use of Removable Boot vs Cast After Ankle Surgery: Cost-Effectiveness vs QoL
In a unique combined study, researchers from multiple institutions across the United Kingdom compared a removable boot with plaster cast for the treatment of ankle fractures 2 weeks after surgery with weight bearing as able. They used data from 243 trial participants and reviewed medical notes to estimate costs from both the National Health Service (NHS) and…
TAA in Patients Age <50: Midterm Outcomes
In a chart review that spanned 2000-2017, researchers from Duke University looked at 58 patients who underwent primary total ankle arthroplasty (TAA) (average age at surgery 43.3 years) and had minimum clinical follow-up of 5 years. They found that 11 required additional surgery related to the TAA; 6 patients (10.3%) required bone grafting of peri-implant…
Prediabetes Patients Prefer Lifestyle Interventions
In the age of personalized medicine, clinicians are trying to better understand not only patient preferences and values, but expectations as well. This systematic review examined 18 studies involving 17,240 patients with prediabetes to spot trends to facilitate clinical decision-making about how best to prevent disease progression.
Caprini Risk Score & Varicose Vein Ablation
The incidence of venous thromboembolism after ablation of superficial varicose veins is 3.4%, predominantly due to asymptomatic endovenous heat-induced thrombosis (EHIT) and deep vein thrombosis (DVT), and significantly correlates with the Caprini Risk Score.
Study to Reduce Incidence of Knee OA Recruitment To Start 2/2024
Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, a 48-month program of dietary weight loss and exercise will result in less incident structural knee OA compared to control.
Yet Another Reason NOT To Be Sedentary
Based on data from nearly 50,000 adults in the United Kingdom, researchers from the U.S. National Institutes of Health have shown an association between dementia risk and daily sedentary behavior. Though the study cannot establish a causal link, it does support the idea that more time spent not moving–such as…
Hip Therapy Tempers Low Back Pain, Aids Gait Speed
Hip-focused physical therapy for older adults with chronic low back pain, hip pain, and hip muscle weakness may offer promise to address pain-related disability and functional limitations. NIA-funded scientists recently conducted a clinical trial comparing hip- versus back-focused therapies.
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