Ankle fractures are common among healthy adults, but even moreso among elderly patients. And the population of so-called Baby Boomers (today’s 60–78-year-olds) is expected to nearly double by 2050. Ankle fractures in patients with osteopenia and in diabetic patients with deranged bone remodeling constitute high-risk injuries that may result in catastrophic complications.

Noting a lack of evidence-based guidance on mobility challenges in individuals with neuropathic conditions, in particular Charcot-Marie-Tooth (CMT) disease and Cerebral Palsy (CP), researchers from the University of Iowa in Iowa City identified a critical need for a better understanding of how surgical correction affects mobility, balance confidence, and gait compared to ankle-foot-orthosis (AFO) bracing.

Shin splints are a label often given for shin pain, but this is NOT a diagnosis as several conditions can cause pain in this region. So here are some of the common causes; Front of shin: Anterior exertional compartment syndrome, Tibial stress fracture. Inside of shin: Medial tibial stress syndrome (MTSS), Tibial stress fracture, Deep posterior exertional compartment syndrome, Calf muscle strain (soleus or gastrocnemius).

The presence of peripheral artery disease (PAD) in patients with diabetic foot ulcers (DFUs) is a significant risk factor for chronicity and amputation. Ankle–brachial pressure index (ABPI) is a screening tool for PAD. Brachial systolic pressure measurement, used as a denominator in the calculation of…

High Preload increases shortening work, explains ~2/3 of the SSC-effect BUT despite identical preload and tendon-based passive elastic behavior less work in MATCHED compared to SSC. Stretch-induced intramuscular Force enhancement conveys to the shortening phase of SSC, explains ~1/3 of the SSC-effect. Stretch-induced increased performance in SSCs is attributed to passive-elastic structures within the contractile element, resulting in higher neuromuscular efficiency.

This study, the first of its kind, aimed to explore the connection between Obstructive Sleep Apnea (OSA) and osteoarthritis (OA) and evaluate causality using Mendelian randomization (MR), utilizing large-scale observational study data and genetic datasets.

More than 200 million people around the world have osteoporosis, and women are at especially high risk after menopause due to declining levels of the hormone estrogen, which helps keep bones strong. While osteoporosis rarely has noticeable symptoms, it can lead to serious injuries when otherwise minor falls cause broken bones that lead…

People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease (AD), according to new research from Washington University School of Medicine in St. Louis. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatments, said…

The Walking Impairment Questionnaire (WIQ) is a common and easy-to-use assessment of walking incapacity in people with claudication due to peripheral artery disease (PAD). It has 4 subscales: pain severity, walking distance, walking speed, and ability to climb stairs. It is one of several clinical measurements useful for predicting patients’ functional limitations, assessing…

Romosozumab, a humanized monoclonal antibody sclerostin inhibitor, was FDA-approved in 2019 for the treatment of osteoporosis in postmenopausal women and men who are at increased risk of fracture. Significantly, the FDA applied a black box warning for the drug noting the potential risk of myocardial infarction, stroke and cardiovascular death.

About 38 million Americans have diabetes, and each year a staggering 154,000 Americans will suffer amputations, roughly 80% of which will be the result of complications from diabetes. Their life expectancy following this procedure is five years; the probability of a second amputation is up to 35%. By comparison, a total of 1,700 American soldiers had limbs removed since 2002 due to injuries sustained during combat tours in…