November 2015

Patient-reported function, kinematics predict response to hip strengthening

In the moment: OA

By Jordana Bieze Foster

Patient-reported function and lower extremity kinematics can predict response to a hip strength­ening intervention in patients with knee osteoarthritis (OA), according to research from the University of Calgary in Alberta, Canada.

Investigators recruited 39 patients with mild to moderate knee OA to complete a six-week hip strengthening intervention, with one supervised session per week plus home exercises an average of 5.5 days per week. The researchers then grouped the patients according to their improvement in symptoms and function after six weeks, based on effect size, and looked for associations between patients’ baseline variables and their response to the intervention.

Patient-reported function in daily living and frontal plane hip kinematics during loading response best differentiated the 11 high responders from the 14 low responders and 14 nonresponders. A combination of hip, knee, and ankle kinematics differentiated low responders from nonresponders.

The combination of predictive factors was able to successfully classify patient response to the hip strengthening inter­vention with an overall accuracy of 85.4%. The findings were published in October by PLoS One.


Kobsar D, Osis ST, Hettinga BA, Ferber R. Gait biomechanics and patient-
reported function as predictors of response to a hip strengthening exercise intervention in patients with knee osteoarthritis. PLoS One 2015;10(10): e0139923.

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