Following on the 2018 ASPREE trial findings that the daily use of aspirin did not improve disability-free survival among aging adults, a new substudy now reports that aspirin (100mg daily) was associated with a higher risk of serious falls (incidence ratio: 1.17; P = 0.01). The researchers recruited…
Lower Extremity Review
Telmisartan Did Not Improve Mobility In Peripheral Arterial Disease
The blood pressure medication telmisartan did not improve walking performance in patients with peripheral arterial disease (PAD) in the lower extremity, according to new research. These results challenge previous studies that found telmisartan improved running strength in mice and…
Blood Flow Restriction Exercise After ACL Reconstruction
It is well known that muscle mass is lost following anterior cruciate ligament reconstruction (ACLR) surgery. These researchers sought to compare muscle strength gain in the quadriceps and hamstring muscles in patients following ACLR surgery using exercises with and without blood flow restriction.
Age-related Muscle Decline Related to Lethal Childhood Disease?
Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy (SMA) may enable development of therapies to curb the muscle decline that accompanies aging, new research suggests.
Smart Bandage Improves Wound Healing in Mice
A smart bandage used wireless power to protect and monitor wounds, provide feedback on tissue health, and encourage healing using electrical current. Mice treated with the bandage healed faster than those protected with standard wound dressings. The skin has a remarkable capacity to…
By the Numbers: Total Ankle Arthroplasty Trends ↗
Use of total ankle arthroplasty (TAA) has been on the rise and researchers from Emory University in Atlanta, Georgia, put the numbers together:
Biomechanical Performance Factors in Sprint Starts
The 100m race is the highlight of many track and field events; indeed, in the Olympic Games, it defines the fastest man and woman in the world. In this event, the block start performance and subsequent first 2 steps can be of critical importance since they directly influence the runner’s overall time.
AACE Algorithm for Diabetic Peripheral Neuropathy
Despite major advances in elucidating the pathogenesis of diabetic peripheral neuropathy (DPN), there remains a lack of disease-modifying treatment options in individuals with diabetes. Currently, there is no convincing evidence supporting glucose control or lifestyle management as therapies for…
Suggested Reading
For 10 years, John O’Sullivan, founder of the Changing the Game Project and Way of the Champions Podcast, has published his books of the year. Here’s what he has to say for 2022…
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