This study provides the first insights into fast and slow muscle fiber transcriptome dynamics with lifelong endurance exercise. The fast fibers were more responsive to exercise with divergent transcriptome signatures among young exercisers (growth and metabolic), lifelong exercisers (metabolic), and old healthy nonexercisers (stress).
Lower Extremity Review
Students’ Backpack Load Impacts Stair Descent Gait
Investigators from Shaanxi Normal University in China studied the impact of increasing backpack load on the gait of adolescents during stair descent. Sixteen healthy male students (age = 12.9 ± 0.6 years) were required to descend the stairs in 4 loaded conditions. The kinematic, kinetic, and EMG data were collected synchronously and gait parameters, especially indicators of balance control, were analyzed.
Low Annual Revision Rate in Ankle Distraction for Ankle Osteoarthritis
Ankle osteoarthritis severely impacts patients’ mental and physical quality of life. Besides total ankle replacement and ankle arthrodesis, ankle distraction has been shown to be a promising alternative. The primary aim of this systematic literature review and meta-analysis was to determine the annual revision rates (ARRs) after ankle distraction.
Cranberry Extract Improves Runners’ Speed
Competitive athletes are always looking for an extra edge to help improve performance. According to a new study by Concordia researchers published in the journal Physical Activity and Nutrition, they can find one in the common cranberry. Cranberries have the highest polyphenol and antioxidant capacity among fruits and vegetables and may protect against exercise-induced free radical production, consequently improving performance.
Changes in Foot Posture in Children with CP
Researchers from the Department of Orthopaedics at the Nemours Children’s Hospital Delaware (Wilmington, DE) wanted to understand the change in dynamic foot posture in children with cerebral palsy. They were able to track 33 children (54 limbs) who completed 16.9 evaluations from an initial age of 2.9 (±0.7) yrs to 18.6 (±1.7) yrs. They found that early valgus foot…
MS More Prevalent Among Black Americans Than Once Thought
According to a new study1 by researchers at the University of Maryland School of Medicine, multiple sclerosis (MS) is more prevalent – particularly among Black Americans – than previously thought. Using de-identified health insurance claims of 96 million adults living in the United States, the research team was able to estimate in more detail how many individuals age 18 and…
Vibration Aids Hard-to-Heal Wounds
A new scoping review from Japan suggests that low-frequency and low-intensity vibration therapies helped effectively treat wounds (including pressure injuries, diabetic foot ulcers, and venous leg ulcers) by improving blood flow, relieving pain, reducing exudate, removing necrotic tissue, and increasing the expression of nitric oxide associated with wound healing.
Exercise + Electrical Simulation for CAI
Chronic ankle instability (CAI) is diagnosed when symptoms (perceptions of the ankle ‘giving way’, pain, weakness, or limited ankle range of motion) have persisted for more than 1 year after an initial lateral ankle sprain. Therapeutic exercise is a key treatment for overcoming neuromuscular deficits in CAI. In this study, researchers from…
High Heels Remodel Leg Muscles
User metabolic power during walking in flat-soled shoes decreased following daily high-heel use. High heels remodel leg muscle-tendons & improve walking economy regardless of footwear condition.
Therapeutic Benefits of Tai Chi Highlighted
The inaugural meeting of the Tai Chi & Qigong as Whole Person Health Conference was held in Boston, MA, in September 2023. It was hosted by the Osher Center for Integrative Medicine and jointly sponsored by the Harvard Medical School and Brigham and Women’s Hospital. Nearly 300 experts, professors, researchers, and professionals from…
Exercise Training Modes Lower Resting Blood Pressure
In an effort to establish an optimal antihypertensive exercise prescription, researchers from Kent, England, conducted a large-scale pairwise and network meta-analysis on the effects of various exercise modes on resting blood pressure. They looked at 270 randomized controlled trials with more than 15,800 patients.
Inflammatory Markers in Diabetic Foot Infections
This meta-analysis of 10 studies with 785 patients confirmed the significant association between diabetic foot infection and 3 inflammatory markers: white blood cell (WBC) count, C-reactive protein (CRP) level, and procalcitonin (PCT) level. The meta-analysis indicated that mean WBC count (standardized mean differences…
Use of Removable Boot vs Cast After Ankle Surgery: Cost-Effectiveness vs QoL
In a unique combined study, researchers from multiple institutions across the United Kingdom compared a removable boot with plaster cast for the treatment of ankle fractures 2 weeks after surgery with weight bearing as able. They used data from 243 trial participants and reviewed medical notes to estimate costs from both the National Health Service (NHS) and…
TAA in Patients Age <50: Midterm Outcomes
In a chart review that spanned 2000-2017, researchers from Duke University looked at 58 patients who underwent primary total ankle arthroplasty (TAA) (average age at surgery 43.3 years) and had minimum clinical follow-up of 5 years. They found that 11 required additional surgery related to the TAA; 6 patients (10.3%) required bone grafting of peri-implant…
Prediabetes Patients Prefer Lifestyle Interventions
In the age of personalized medicine, clinicians are trying to better understand not only patient preferences and values, but expectations as well. This systematic review examined 18 studies involving 17,240 patients with prediabetes to spot trends to facilitate clinical decision-making about how best to prevent disease progression.
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