February 2022

EXERCISE BEATS ESTRADIOL AT PREVENTING TYPE 2 DIABETES IN RATS

Researchers from Augustana University in South Dakota sought to understand the molecular mechanisms by which estradiol and exercise induce beneficial effects by assessing whole body and cellular changes. They divided a group of female rats into groups—control, exercise (Ex), estradiol replacement, and Ex + estradiol. Only exercise effectively reduced white adipose tissue (WAT) weight gain, food intake, blood glucose levels, and serum insulin levels.

Used with permission from: Fritsch LJ, McCaulley SJ, Johnson CR, Lawson NJ, Gorres-Martens BK. Exercise prevents whole body type 2 diabetes risk factors better than estradiol replacement in rats J App Physiol. 2021;131:5;1520-1531.

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