Lower Extremity Review
Physiotherapy researchers from Colombia found that a community-level supervised program of physical activity had significant positive outcomes on the physical capacities of older adults including strength, flexibility, balance, and aerobic capacity.
In a first-of-its-kind study, researchers from the Institute of Neuroscience, Université Catholique de Louvain, Louvain-la-Neuve, Belgium, investigated the regulation of the endocannabinoid system using several exercise paradigms in human skeletal muscle. They also compared endocannabinoid regulation in healthy and…
After an anterior cruciate ligament (ACL) injury, people need secondary prevention strategies to identify osteoarthritis at its earliest stages so that interventions can be implemented to halt or slow the progression toward its long-term burden. The Osteoarthritis Action Alliance formed an interdisciplinary Secondary Prevention Task Group to develop a consensus on…
Using a web-based global survey, an international team of researchers found that COVID-19 had an outsized impact on healthy behaviors in people with disabilities, compared with people without disabilities. The overall impact of COVID-19 pandemic among the 2689 responses with full data available for analysis was reported as…
Meniscal damage results in higher peak stress on the articular cartilage and leads to cartilage degeneration and osteoarthritis. Thus, in recent years there has been an increasing tendency to “save the meniscus” and to repair meniscal defects. However, this is not always possible and restoring meniscal function using scaffolds fulfills this gap.
Determining the effects of early specialization in a specific sport is difficult. Therefore, it is necessary to investigate its effects based on the type of sports. The purpose of this study was to investigate the proportion of participants who had been participating in a single sport, in individual or team sports from an early age and to…
Extreme heat may discourage physical activity of children while shade may provide thermal comfort. The authors determined the associations between ambient temperature, shade, and moderate to vigorous physical activity (MVPA) of children during school recess.
Patients with anterior cruciate ligament injury are at high risk of post-traumatic osteoarthritis and their response to reconstructive surgery and rehabilitation varies. Proteins identified in the orchestration of the acute inflammatory response may be predictive of patient outcomes. These authors used an unbiased, bottom-up proteomics approach…
As medical use of cannabis becomes more common in the treatment of chronic pain, these researchers wanted to better understand the patient perspective of this therapy. Based on semi-structured interviews with 13 chronic pain patients at a hospital-based clinic in Ontario, Canada, patients reported reduced pain…
Researchers from McGill University and Lady Davis Institute for Medical Research in Montreal, Canada, took on the task of examining the ethical considerations physicians face when patients admit to cannabis-impaired driving. As of October 2018, dried forms of cannabis became legal in Canada for adults age 18 and older, and…
As a widely prescribed anti-diabetic drug, metformin (MTF) has been receiving novel attention for its analgesic potential. In the study of the complex etiology of neuropathic pain (NeP), male and female individuals exhibit quite different responses characterized by higher pain sensitivity and greater NeP incidence in women.
Carotid atherosclerosis is the leading cause of ischemic stroke. Carotid intima–media thickness (cIMT) is a validated surrogate marker of atherosclerosis that is independently associated with the risk for cardiovascular disease. It’s presence in the general population has been well documented, with one study showing that…
A unique collaboration between imaging science, vascular medicine, and rehabilitation at Vanderbilt University Medical Center (VUMC) is transforming the diagnosis and treatment of lipedema, a debilitating, abnormal deposition of fatty tissue that afflicts an estimated 17 million women in the United States.
Following on the 2018 ASPREE trial findings that the daily use of aspirin did not improve disability-free survival among aging adults, a new substudy now reports that aspirin (100mg daily) was associated with a higher risk of serious falls (incidence ratio: 1.17; P = 0.01). The researchers recruited…
The blood pressure medication telmisartan did not improve walking performance in patients with peripheral arterial disease (PAD) in the lower extremity, according to new research. These results challenge previous studies that found telmisartan improved running strength in mice and…
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