Aerobic exercise effectively reverses the decline in endurance capacity and mitigates muscle atrophy in aged mice. It inhibits CCN2 secretion from senescent muscle stem cells, thereby enhancing skeletal muscle regeneration and preventing fibrosis in aged mice. AICAR supplementation mimics the beneficial effects of aerobic exercise.
Lower Extremity Review
Does Texting While Walking Affect Gait’s Plantar Pressure Parameters?
This study aims to examine the possible effects of mobile phone use on plantar pressure and spatiotemporal parameters during walking. Materials and methods: Thirty volunteers (18 males and 12 females) participated in the study. A 10-m walking path was prepared, and a messaging connection was established. Volunteers were asked to write 3 posts without word or character mistakes and to walk on the path as much as…
Smartphone Usage Negatively Impacts Standing Postural Balance
Researchers from Arizona State University and Carnegie Mellon University have found that modern smartphone usage can negatively impact standing postural balance—and that impact varies by the type of ground condition. They had 16 healthy young individuals perform 2 tasks on their smartphones while standing on 4 different types of ground surfaces…
Does Occupation Footwear Influence Slip Response?
This study investigated how walking in occupational footwear (OF) affects slip outcome and slip recovery strategies in response to an unexpected slip. Participants walked along a walkway while either barefoot (BF; n = 13) or in OF (n = 12). The first five walking trials consisted of the no-slip condition, where a high friction sheet was…
Minimalist School Shoes Improve Intrinsic Foot Muscle Size, Strength, Arch Integrity
Minimalist walking shoes have been shown to improve foot muscle size and strength in active adults, but not in previous studies involving children, which could relate to the more structured footwear used in this study. Hence, this study examined the effects of true minimalists on intrinsic foot muscle size and strength, foot arch integrity…
2MTIR vs PR for Achilles Tendon Rupture
Acute closed midsubstance Achilles tendon rupture (ACMATR) is common, with various treatment methods developed over time. These authors retrospectively compared the 2 mini transverse-incision repair (2MTIR) with percutaneous repair (PR) to determine which method yields better results.
Curcumin Alleviates Osteoarthritis Through the P38MAPK Pathway
A recent report in the Journal of Inflammation Research found that curcumin modulates chondrocyte oxidative stress, inhibits OA inflammation, and inhibits phosphorylation of the p38/MAPK pathway; the model used Sprague-Dawley rats. It also inhibits chondrocyte apoptosis and matrix degradation while promoting cartilage repair through…
Lateral Ankle Ligament Repair Lets Older Adults Remain Active
Researchers from Emory University School of Medicine recently reported that the annual incidence of lateral ankle ligament repair (LALR) has been on the rise since 2009, particularly among those over 70 years of age. They queried the IBM Watson Health Market Scan Database for patients who underwent LALR from January 2009 to…
Reducing Prosthetic Stiffness Can Improve Running in Females with Leg Amputations
Similar to nonamputees, female athletes with unilateral transtibial amputation (TTA) using running-specific leg prostheses (RSPs) may have worse running economy and higher rates of running-related injury than male athletes. These authors hypothesized that optimizing RSP configuration for female athletes could improve running economy and…
Broström-Gould Procedure: 5-Year Follow-Up
Ankle sprains are a common musculoskeletal injury among the general population and often involve the lateral ligament complex. Although the majority of ankle sprains are treated successfully with nonsurgical conservative measures, an estimated 5% to 20% of ankle injuries ultimately develop chronic lateral ankle instability (CAI).
Long-Term Follow-Up Assesses Efficacy of Fosravuconazole for Onychomycosis in Elderly
Onychomycosis is a chronic and intractable disease whose prevalence increases during aging. In elderly patients, if onychomycosis is left untreated and progresses to a severe stage, it may cause functional decline of the lower limbs due to foot pain. This could lead to a decline in activities of daily living and secondary impairment such as cognitive decline.
Pediatric Hurdling Injuries
Hurdling is a unique track event due to a combination of running and jumping over an apparatus. Since hurdling requires a special skillset with sprinting and jumping, athletes are at risk for various musculoskeletal injuries. These authors noted a paucity of studies describing the epidemiology of pediatric hurdle injuries and sought to examine…
Some MS Therapies May Not Slow Disability Progression
In people with primary progressive multiple sclerosis (MS), a new study has found no difference in the amount of time before disability worsened between people taking certain medications and those not receiving treatment. The study was published in a recent issue of the journal Neurology®, the medical journal of the American Academy of Neurology.
NATA Study Highlights Overuse Injuries in High School Sports
Participation in high school sports has physical, physiological, and social development benefits, but it also increases the risk of acute and overuse injuries. Risk of sport-related overuse injury differs between boys and girls. These authors sought to investigate differences in overuse injuries among high school athletes participating in the…
Goal-Directed Osteoporosis Treatment: ASBMR/NHOF Task Force Position Statement 2024
The overarching goal of osteoporosis management is to prevent fractures. A goal-directed approach to long-term management of fracture risk helps ensure that the most appropriate initial treatment and treatment sequence is selected for individual patients. Goal-directed treatment decisions require assessment of clinical fracture history…
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