The ArtAssist, a home-use device for treating peripheral arterial disease (PAD), applies intermittent pneumatic compression to the foot, ankle, and calf. The compression regimen is designed to simulate the vascular benefits of brisk walking, but without pain. The arterial pump technology increases distal blood flow mechanically and by promoting arteriogenesis, the opening of collateral vessels that bypass obstructed arteries. The device is intended for patients with PAD, ischemic diabetic foot ulcers, arterial ulcers, intermittent claudication, or rest pain. Typical usage is three hours per day for at least three months.