Ovation Medical has introduced the new Game Changer Premium Universal OA Knee Brace, designed to get knee osteoarthritis patients back to as much activity as possible. The brace should be worn for 30 to 60 minutes on the first day, and wear time should be gradually increased as comfortable each day thereafter. Every brace comes with printed instructions for use. The company also provides free step-by-step video instructions on its website. Although the best outcomes will be achieved when the Game Changer is worn directly against the skin, it can be effective when worn either under or over clothes.