June 2017

Shriners—St. Louis opens MSK lab

Shriners Hospitals for Children— St. Louis in May celebrated the official opening of its research lab focusing on regenerative medicine and pediatric musculoskeletal research.

A Shriners’ research team lead by Farshid Guilak, PhD, professor of orthopedic surgery at Washington University in St. Louis, in 2016 created a 3D, biodegradable synthetic scaffold made from autologous stem cells that is molded into the shape of a hip joint as a substitute for conventional implants.

Guilak and his team are also combining this SMART (stem cells modified for autonomous regenerative therapy) cell technology with gene therapy in a strategy that could prompt the body to release anti-inflammatory molecules to combat degenerative musculoskeletal diseases.

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- Emily Delzell

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