Researchers at Queen Mary University of London have developed a new organ-on-a-chip model of the human synovium, a membrane-like tissue that lines the joints. The model could help researchers to better understand the mechanisms of arthritis, such as knee osteoarthritis, and to develop new treatments for this group of debilitating diseases.
Lower Extremity Review
Video Education and Knee Osteoarthritis
Patient education is the most commonly used intervention for chronic disease management. Education interventions have variably been shown to have benefits for chronic disease management in general and musculoskeletal pain disorders…
By Thorlene Egerton, Joanne Bolton, Camille E. Short, and Kim L. Bennell
An Osteoarthritis Action Alliance Consensus Statement: Preventing Osteoarthritis After an Anterior Cruciate Ligament Injury
After an anterior cruciate ligament (ACL) injury, people need secondary prevention strategies to identify osteoarthritis at its earliest stages so that interventions can be implemented to halt or slow the progression toward its long-term burden. The Osteoarthritis Action Alliance formed an interdisciplinary Secondary Prevention Task Group to develop a consensus on…
Running Does Not Increase Risk of Arthritis
Chicago Marathon® participants helped orthopedic researchers further understand the impact of long-distance running on bone and joint health, specifically knee and hip arthritis in recreational runners. Results from the largest survey of marathon runners ever conducted showed no association between cumulative running history and the risk for arthritis.
Recommendations for Targeted Strength Training in Rheumatoid Arthritis
A recently published scoping review of strength training recommendations for patients with rheumatoid arthritis included numerous suggestions for encouraging patients. Of note for LER readers…
Tissue Microenvironment in Rheumatoid Arthritis
The recent advance in treatments for rheumatoid arthritis (RA) has significantly improved the prognosis of RA patients. However, these novel therapies do not work well for all RA patients. The unmet need suggests that the current understanding about how inflammatory response arises and progresses in RA is limited. Recent accumulating evidence reveals an important role for the tissue microenvironment in the pathogenesis of RA.
New Knee Osteoarthritis Book from Noigroup
Epiphaknee: A Modern Approach to Knee Osteoarthritis is a new book written by 3 internationally renowned pain and movement experts: G. Lorimer Moseley, DSc, PhD, FAAHMS, FPMANZCA, FACP; David Butler, Ed D, B Phty, GDAMT, M App Sc, PT; and Tasha R. Stanton, BScPT, MSc, PhD.
Lifestyle and Integrative Medicine Strategies for Managing Knee Osteoarthritis
Osteoarthritis (OA) is a slowly evolving articular disease that affects the underlying bone, soft tissue, and synovial fluid.1 Osteoarthritis typically affects the hands and large weight-bearing joints, such as the hips and knees.
By Ziya “Z” Altug, PT, DPT, MS, OCS
OBESITY-RELATED BURDEN OF OSTEOARTHRITIS OF KNEE AND HIP
Osteoarthritis (OA) is a leading cause of disability and a source of societal costs among older adults, especially with an increasingly obese population. Few studies have investigated the burden of knee and hip OA due to high body mass index (BMI).
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